| 1. | Inhibitory effects of beta - elemene cooperating with anti - cd3 anti - glioma bispecific antibodies on growth of neuroglioma 抗胶质瘤双特异性抗体抑制神经胶质瘤生长 |
| 2. | This means when the bispecific antibody binds to healthy tissues away from light , it cannot activate t - cells , resulting in far fewer side effects 这就是说,当双功能抗体与远离光线的健康组织结合时,它不会激活t细胞,这样就极少由副作用。 |
| 3. | Fortunately , recently widely used bispecific antibody technique provided us a good model for target rca blocking for it ' s dual antigen binding activity and for the availablity of high 为了进一步探讨用基因工程的方法制备抗病毒双特异性抗体的可能性,我们又在现有的条件下构建、表达了 |
| 4. | Objection : this study is to prepare a kind of bispecific antibody of anti - hiv p24 antigen and anti - human rbc type a antigen , and to build a new way to detect hiv p24 antigen with this bispecific antibody 目的:制备抗hivp24和抗人a型红细胞双特异性抗体,建立检测hivp24抗原的新方法。 |
| 5. | After the surgeon has removed the bulk of a tumour , the patient could then be injected with bispecific antibodies and a light shone at the affected area which would target the patient ' s own immune system to the tumour site 手术移出肿块后,给病人注射双功能抗体和用光照射易受影响的区域,这个区域能使病人自身免疫系统靶向肿瘤位点。 ” |
| 6. | Therefore the hybrid - hybridoma can secrete not only bispecific antibody but also anti - human rbc type a monospecific antibody and probably anti - p24 monospecific antibody . the mixed antibodies purified by ammonium sulfate is further purified by p24 affinity chromatography . the unsp 这样,分离出双特异性抗体,并证实杂交杂交瘤除分泌抗p24和人红细胞的双特异性抗体外,还分泌抗p24单特异性抗体和抗人a型红细胞单特异性抗体。 |
| 7. | This bispecific antibody companied with another anti - p24 monospecific monoclonal antibody can build a new way of indirect rbc agglutination to detect p24 antigen , and this new way is preliminarily applied to detect serial diluted p24 to determine the sensitivity 用双特异性抗体致敏人a型红细胞做指示剂,以抗p24单特异件单克隆抗体9a7做交联剂,建立间接血凝检测p24抗原的新方法,并初步应用于检测系列稀释的p24抗原以确定测定的敏感性。 |
| 8. | The bispecific antibody tilers of ascites fluid and culture supernatant of 3 - hn are 1 : 16000 and 1 : 64 . at the same time the anti - p24 antibody and the anti - human rbc type a antibody in the ascites fluid of hybrid - hybridoma 3 - hn are tested , and their titer is 1 : 800 and 1 : 16000 respectively 为89士9条j十; ;的腹水型和上清型双特异性抗体的效价分别为1 : 16000和1 : 64 ,同时测定腹水型抗体抗p24抗体活性及抗人a型红细胞凝集抗体活性,效价分别为1 : 800和1 : 16000 。 |
| 9. | To answer this question , a bispecific , trifunctional antibody constructs which can not only target block virus incorporated rca , but also can induce complement activation by it ' s fc fragment were designed and constructed and iv the role of this kind of bispecific antibody in virus neutralization was studied . 1 . to test our idea , human immunodeficient virus ( hiv ) and enveloped extracellular virus ( eev ) of vaccinia virus ( vv ) were selected in our study because of their complex immune evasion stratiges , their threaten to humans , and because both these two kinds of virus can escape complement attack by incorporating host rca into their envelope 以严重危害人类健康,且具有复杂免疫逃避机制的有包膜的hiv病毒及痘苗病毒的eev病毒为研究对象,首先对它们逃避补体攻击的现象进行了验证,探讨了宿主膜补体调节蛋白cd55 、 cd59与hiv病毒及eev病毒免疫逃避的关系,评价了病毒结合的这两种补体调节蛋白作为本研究提出的,通过消除病毒逃避补体攻击的机制来恢复病毒对补体攻击的敏感性,提高补体抗病毒效率这一抗病毒策略的靶点的可能性。 |
| 10. | The ascites fluid antibody purified by 33 % ammonium sulfate is further purified by chromatography . the p24 affinity chromato - graphic column done to purify the bispecific antibody is in the brcn activated sepharose 4b . after washing the unspecific proteins , change the washing buffer and the anti - p24 / anti - human rbc type a bispecific antibody and the anti - p24 monospecific antibody are gained respectively 方法是先用硫酸绥盐析,再过亲和层析柱,即33饱和硫酸按沉淀后,透祈过夜,上p24抗原做配体的滨化氰活化的sepharose4b柱,流洗掉杂蛋白和抗人红细胞单特异性抗体后,再洗脱并收集双特异性抗体。 |